PPP1R12C

Across TCGA patient cohorts, PPP1R12C protein abundance is significantly associated with the RNA expression of many other genes, with 21,488 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1R12C-associated genes across cancer lineages are RHOJ, EMCN, and LHFPL6. Each is linked with PPP1R12C in more than 9 cancer types. Because this analysis shows association rather than direction, both PPP1R12C-to-partner and partner-to-PPP1R12C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R12C versus RHOJ in UCEC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R12C→partner) and Y-score (partner→PPP1R12C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RHOJ →	+1.033	+0.453	<.001	<.001	3	10
UCEC	EMCN →	+1.097	+0.484	<.001	<.001	3	10
OV	LHFPL6 →	+1.222	+0.350	<.001	<.001	3	10
OV	SRPX →	+1.448	+0.366	<.001	<.001	3	9
GBM	MEOX2 →	+2.395	+0.190	<.001	<.001	3	9
CCRCC	ASPA →	+1.211	+0.141	.001	.007	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,488 associations by consensus.

PPP1R12C vs RHOJ — UCEC

Explore this scatter interactively →