PPP1R12C

Across TCGA cell cohorts, PPP1R12C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,623 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PPP1R12C-associated GO terms across cancer lineages are Endosomal transport, Negative regulation of calcium ion export across plasma membrane, and Ascending thin limb development. Each is linked with PPP1R12C in more than 14 cancer types. Because this analysis shows association rather than direction, both PPP1R12C-to-partner and partner-to-PPP1R12C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by PPP1R12C-low versus PPP1R12C-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R12C→partner) and Y-score (partner→PPP1R12C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endosomal transport →	+0.077	+0.957	<.001	.001	3	15
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.100	+1.028	<.001	<.001	3	15
SKIN	Ascending thin limb development →	+0.338	+0.936	.008	.001	3	14
SKIN	Metanephric ascending thin limb development →	+0.338	+0.936	.008	.001	3	14
BONE	Cytosolic transport →	+0.064	+0.875	.003	<.001	3	13
OESOPHAGUS	Negative regulation of protein-containing complex assembly →	+0.097	+0.978	.003	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,623 associations by consensus.

Endosomal transport by PPP1R12C expression — BONE

Explore this box plot interactively →