PPP1R12A-AS1

Across TCGA pan-cancer cohorts, PPP1R12A-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PPP1R12A-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PPP1R12A-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PPP1R12A-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

KIRC, UCS, and MESO are the cancer types where PPP1R12A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.704	0.557	<.001	55	view →
UCS	DFS	Tertile	II,III,IV	0.565	0.158	.001	46	view →
MESO	DFS	Tertile	All	0.281	0.465	.014	37	view →
PAAD	DFS	Quartile	All	0.557	0.270	.007	21	view →
READ	OS	Median	III,IV	0.724	0.267	.001	15	view →
SKCM	OS	Median	IV	0.867	0.225	.001	14	view →
THCA	DFS	Quartile	II,III,IV	0.197	0.775	.012	12	view →
LUAD	DFS	Tertile	All	0.235	0.422	.009	12	view →
LGG	OS	Median	All	0.925	0.864	.007	11	view →
LUSC	DFS	Quartile	All	0.505	0.317	.030	9	view →
CESC	DFS	Median	All	0.456	0.632	.037	8	view →
KIRP	DFS	Tertile	All	0.913	0.639	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PPP1R12A-AS1–KIRC (OS)

Open the KIRC breakdown →