Across TCGA pan-cancer cohorts, PPP1R10 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PPP1R10 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PPP1R10 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP1R10 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

HNSC, LSCC, and LUAD are the cancer types where PPP1R10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.215	0.810	.005	32	view →
LSCC	OS	Quartile	II,III,IV	0.944	0.618	.010	18	view →
LUAD	DFS	Median	III,IV	0.744	0.263	.009	16	view →
PDAC	DFS	Quartile	III,IV	0.884	0.344	.017	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: PPP1R10 tumor-vs-normal RNA expression · all PPP1R10 data types