Across TCGA patient cohorts, PPP1R10 mutation is significantly associated with the RNA expression of many other genes, with 2,724 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R10-associated genes across cancer lineages are ERI2, RN7SKP208, and OIP5. Each is linked with PPP1R10 in more than 3 cancer types. Because this analysis shows association rather than direction, both PPP1R10-to-partner and partner-to-PPP1R10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R10→partner) and Y-score (partner→PPP1R10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERI2 →	+0.424	+4.119	<.001	<.001	3	3
HNSC	RN7SKP208 →	+0.178	+4.716	<.001	.003	3	3
UCEC	OIP5 →	+0.643	+3.169	<.001	<.001	3	3
UCEC	SDHB →	+0.332	+1.999	.002	<.001	3	3
UCEC	FAM199X →	+0.381	+1.703	.009	.006	3	3
UCEC	MPHOSPH6 →	+0.563	+1.999	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,724 associations by consensus.

Exploration

PPP1R10 survival (RNA) · tumor vs normal (RNA) · all PPP1R10 data types