Across TCGA patient cohorts, PPP1R10 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R10-associated genes across cancer lineages are eIF4E, Rad50, and Caspase-7-cleavedD198. Each is linked with PPP1R10 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R10-to-partner and partner-to-PPP1R10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R10→partner) and Y-score (partner→PPP1R10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.181	+2.807	.008	.003	3	2
UCEC	Rad50 →	-0.165	-1.794	.036	.024	3	2
UCEC	Caspase-7-cleavedD198 →	+0.417	+1.697	.030	.012	3	2
UCEC	4E-BP1 →	+0.321	+2.807	<.001	.002	3	2
BLCA	SETD2 →	-0.172	-3.321	.032	.010	3	1
BLCA	Smac →	+0.276	+2.858	.024	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

PPP1R10 survival (RNA) · tumor vs normal (RNA) · all PPP1R10 data types