Across TCGA cell cohorts, PPP1R10 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R10-associated genes across cancer lineages are MPC1L, OR5M8, and ADH1A. Each is linked with PPP1R10 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R10-to-partner and partner-to-PPP1R10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R10→partner) and Y-score (partner→PPP1R10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	MPC1L →	+0.083	+5.087	<.001	.004	3	1
CNS	OR5M8 →	+0.013	+4.169	<.001	.008	3	1
CNS	ADH1A →	+0.051	+3.774	.007	.008	3	1
CNS	CCER1 →	+0.009	+4.169	<.001	.008	3	1
CNS	PRAMEF7 →	+0.109	+4.169	<.001	.008	3	1
CNS	PRAMEF5 →	+0.275	+4.169	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

PPP1R10 survival (RNA) · tumor vs normal (RNA) · all PPP1R10 data types