PPM1J

Across TCGA patient cohorts, PPM1J protein abundance is significantly associated with the protein abundance of many other proteins, with 10,991 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPM1J-associated proteins across cancer lineages are NBN_S432, NCF2_S332, and SH3GL1_S288. Each is linked with PPM1J in more than 3 cancer types. Because this analysis shows association rather than direction, both PPM1J-to-partner and partner-to-PPM1J results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPM1J versus NBN_S432 in UCEC, with a Pearson correlation of -0.53.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1J→partner) and Y-score (partner→PPM1J) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NBN_S432 →	-1.061	-0.915	<.001	<.001	3	4
UCEC	NCF2_S332 →	-2.927	-1.809	<.001	<.001	3	4
PDAC	SH3GL1_S288 →	-1.658	-1.797	<.001	<.001	3	4
PDAC	SH3PXD2A_S722 →	+1.241	+1.640	<.001	<.001	3	4
LUAD	SLC4A1AP_S82 →	-2.105	-1.454	.001	<.001	3	4
UCEC	SRSF11_S449 →	-2.446	-1.008	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,991 associations by consensus.

PPM1J vs NBN_S432 — UCEC

Explore this scatter interactively →