PPM1F

Across TCGA cell cohorts, PPM1F RNA expression is significantly associated with the go_rna of many other GO terms, with 5,159 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPM1F-associated GO terms across cancer lineages are Protein depolymerization, Caveolin-mediated endocytosis, and Phosphatidylinositol biosynthetic process. Each is linked with PPM1F in more than 14 cancer types. Because this analysis shows association rather than direction, both PPM1F-to-partner and partner-to-PPM1F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein depolymerization grouped by PPM1F-low versus PPM1F-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1F→partner) and Y-score (partner→PPM1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protein depolymerization →	+0.149	+1.568	<.001	<.001	3	15
OVARY	Caveolin-mediated endocytosis →	+0.211	+1.034	<.001	<.001	3	15
KIDNEY	Phosphatidylinositol biosynthetic process →	+0.061	+0.958	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Positive regulation of focal adhesion assembly →	+0.182	+1.246	<.001	<.001	2	15
KIDNEY	Symbiont-mediated disruption of host cellular anatomical structure →	+0.147	+0.815	<.001	<.001	3	14
KIDNEY	Symbiont-mediated disruption of host anatomical structure →	+0.147	+0.815	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,159 associations by consensus.

Protein depolymerization by PPM1F expression — BREAST

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