PPIP5K1

Across TCGA patient cohorts, PPIP5K1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,714 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPIP5K1-associated proteins across cancer lineages are PPIP5K1_S944, TP53BP1, and PPIP5K1_S987. Each is linked with PPIP5K1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PPIP5K1-to-partner and partner-to-PPIP5K1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIP5K1 versus PPIP5K1_S944 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIP5K1→partner) and Y-score (partner→PPIP5K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPIP5K1_S944 →	+0.480	+0.571	<.001	<.001	3	7
BRCA	TP53BP1 →	+0.401	+0.801	<.001	<.001	3	6
PDAC	PPIP5K1_S987 →	+0.686	+0.461	.001	.004	3	6
LUAD	SNAP23 →	+0.312	+0.437	<.001	<.001	3	5
BRCA	HDLBP →	-0.243	-0.634	<.001	<.001	3	5
HNSC	IGF1R →	+0.458	+0.447	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,714 associations by consensus.

PPIP5K1 vs PPIP5K1_S944 — LSCC

Explore this scatter interactively →