PPIP5K1

Across TCGA patient cohorts, PPIP5K1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,721 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPIP5K1-associated genes across cancer lineages are CCNDBP1, CKMT1B, and CATSPER2. Each is linked with PPIP5K1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PPIP5K1-to-partner and partner-to-PPIP5K1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIP5K1 versus CCNDBP1 in COAD, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIP5K1→partner) and Y-score (partner→PPIP5K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CCNDBP1 →	+0.651	+0.464	<.001	<.001	3	7
LSCC	CKMT1B →	+0.938	+0.233	<.001	<.001	3	7
UCEC	CATSPER2 →	+0.534	+0.261	.004	.002	3	7
OV	CHP1 →	+0.711	+0.445	.002	.003	3	5
HNSC	CKMT1A →	+1.021	+0.504	<.001	<.001	3	5
BRCA	SPINT1-AS1 →	+0.589	+0.268	.002	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,721 associations by consensus.

PPIP5K1 vs CCNDBP1 — COAD

Explore this scatter interactively →