PPIP5K1

Across TCGA patient cohorts, PPIP5K1 mutation is significantly associated with the RNA expression of many other genes, with 1,892 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPIP5K1-associated genes across cancer lineages are RNU7-90P, ABALON, and MIR7702. Each is linked with PPIP5K1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPIP5K1-to-partner and partner-to-PPIP5K1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-90P grouped by PPIP5K1-low versus PPIP5K1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIP5K1→partner) and Y-score (partner→PPIP5K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU7-90P →	+0.140	+3.212	<.001	.005	3	2
SKCM	ABALON →	+0.520	+2.813	.003	.001	3	2
UCEC	MIR7702 →	+0.229	+4.253	<.001	.004	3	2
UCEC	E2F1 →	+0.875	+3.223	.003	.009	3	2
SKCM	NUP93 →	+0.826	+2.851	<.001	.001	3	2
SKCM	VAC14 →	+0.656	+2.826	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,892 associations by consensus.

RNU7-90P by PPIP5K1 expression — SKCM

Explore this box plot interactively →