PPIAP80

Across TCGA patient cohorts, PPIAP80 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,738 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAP80-associated GO terms across cancer lineages are Ribosomal large subunit assembly, tRNA 5'-end processing, and Mitochondrial respiratory chain complex assembly. Each is linked with PPIAP80 in more than 13 cancer types. Because this analysis shows association rather than direction, both PPIAP80-to-partner and partner-to-PPIAP80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal large subunit assembly grouped by PPIAP80-low versus PPIAP80-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP80→partner) and Y-score (partner→PPIAP80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ribosomal large subunit assembly →	+0.044	+0.196	.001	<.001	2	14
STAD	tRNA 5'-end processing →	+0.039	+0.222	<.001	<.001	2	12
STAD	Mitochondrial respiratory chain complex assembly →	+0.046	+0.197	<.001	<.001	2	11
ESCA	Pyrimidine ribonucleoside triphosphate biosynthetic process →	+0.052	+0.266	<.001	<.001	3	10
STAD	Protein maturation by iron-sulfur cluster transfer →	+0.055	+0.215	<.001	<.001	3	9
STAD	Protein import into mitochondrial matrix →	+0.034	+0.173	.002	.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,738 associations by consensus.

Ribosomal large subunit assembly by PPIAP80 expression — STAD

Explore this box plot interactively →