PPIAP80

Across TCGA pan-cancer cohorts, PPIAP80 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated PPIAP80 data layer compared with 2 for mutation status.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PPIAP80 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPIAP80 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CESC show a favorable association.

STAD, ACC, and SKCM are the cancer types where PPIAP80 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	III,IV	0.232	0.468	<.001	109	view →
ACC	DFS	Quartile	All	0.310	0.766	<.001	93	view →
SKCM	OS	Tertile	II,III,IV	0.889	0.817	.003	65	view →
MESO	OS	Tertile	III,IV	0.318	0.660	.001	51	view →
UCEC	DFS	Tertile	All	0.833	0.916	<.001	48	view →
BRCA	DFS	Median	II,III,IV	0.504	0.544	.001	39	view →
THCA	DFS	Quartile	IV	0.559	0.880	<.001	37	view →
THYM	DFS	Tertile	All	0.683	0.944	.007	22	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	18	view →
PRAD	DFS	Tertile	All	0.834	0.900	.039	18	view →
LIHC	DFS	Tertile	All	0.461	0.567	.032	12	view →
COAD	DFS	Tertile	IV	0.337	0.568	.024	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

PPIAP80–STAD (DFS)

Open the STAD breakdown →