PPIAP80

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PPIAP80 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPIAP80-associated genes across cancer lineages are Endothelial cells and lymphatic Endothelial cells. Each is linked with PPIAP80 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPIAP80-to-partner and partner-to-PPIAP80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by PPIAP80-low versus PPIAP80-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP80→partner) and Y-score (partner→PPIAP80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEndothelial cells →-0.045-3.127.033.02011
UCEClymphatic Endothelial cells →-0.028-3.116.034.02011
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Endothelial cells by PPIAP80 expression — UCEC

Box plot of Endothelial cells in PPIAP80-low vs PPIAP80-high samples in UCEC.

Explore this box plot interactively →

Exploration