PPIAP75

Across TCGA patient cohorts, PPIAP75 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,992 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PPIAP75-associated proteins across cancer lineages are RPS6KA4, TYMP, and UCHL1. Each is linked with PPIAP75 in more than 3 cancer types. Because this analysis shows association rather than direction, both PPIAP75-to-partner and partner-to-PPIAP75 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIAP75 versus RPS6KA4 in HNSC, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP75→partner) and Y-score (partner→PPIAP75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPS6KA4 →	-0.400	-0.763	<.001	.007	3	4
HNSC	TYMP →	-0.443	-0.689	<.001	.001	3	3
LSCC	UCHL1 →	+1.214	+0.458	<.001	.007	3	3
LUAD	N4BP1_S300 →	-0.418	-0.377	<.001	.002	3	3
HNSC	BMP2K →	-0.245	-0.652	<.001	.002	3	3
OV	DSG2_S700 →	+1.056	+0.395	.005	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,992 associations by consensus.

PPIAP75 vs RPS6KA4 — HNSC

Explore this scatter interactively →