PPIAP75

Across TCGA pan-cancer cohorts, PPIAP75 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated PPIAP75 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher PPIAP75 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP75 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

LIHC, UVM, and UCS are the cancer types where PPIAP75 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.588	0.746	<.001	61	view →
UVM	OS	Median	II,III,IV	0.669	0.902	.014	56	view →
UCS	OS	Tertile	III,IV	0.332	0.745	.004	42	view →
HNSC	OS	Median	IV	0.782	0.629	.002	41	view →
ACC	OS	Median	All	0.786	0.948	<.001	35	view →
PAAD	OS	Quartile	All	0.788	0.350	.001	27	view →
MESO	DFS	Quartile	All	0.964	0.396	.007	24	view →
LUAD	OS	Tertile	III,IV	0.441	0.817	<.001	24	view →
KICH	OS	Quartile	All	0.521	0.926	.003	17	view →
KIRP	OS	Median	III,IV	0.727	0.202	.016	15	view →
STAD	DFS	Median	II,III,IV	0.376	0.640	.007	15	view →
LUSC	OS	Quartile	II,III,IV	0.879	0.463	.007	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

PPIAP75–LIHC (OS)

Open the LIHC breakdown →