PPIAP64

Across TCGA patient cohorts, PPIAP64 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,121 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPIAP64-associated proteins across cancer lineages are STIM1_S257, ZNF830, and SMARCC2. Each is linked with PPIAP64 in more than 4 cancer types. Because this analysis shows association rather than direction, both PPIAP64-to-partner and partner-to-PPIAP64 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIAP64 versus STIM1_S257 in PDAC, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP64→partner) and Y-score (partner→PPIAP64) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	STIM1_S257 →	-0.771	-0.426	<.001	<.001	3	5
PDAC	ZNF830 →	+0.289	+0.416	<.001	<.001	3	4
GBM	SMARCC2 →	+0.250	+0.490	.001	.002	3	4
GBM	VEZF1 →	+0.534	+0.875	<.001	<.001	3	4
HNSC	RANBP10_S369 →	-0.506	-0.553	<.001	<.001	3	4
CCRCC	SEC63_T537 →	-0.932	-0.514	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,121 associations by consensus.

PPIAP64 vs STIM1_S257 — PDAC

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