PPIAP64

Across TCGA pan-cancer cohorts, PPIAP64 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated PPIAP64 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher PPIAP64 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PPIAP64 expression acts as an unfavorable survival marker, although some lineages such as KIRP and UCS show a favorable association.

KIRP, STAD, and UVM are the cancer types where PPIAP64 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	III,IV	0.702	0.250	<.001	85	view →
STAD	OS	Quartile	III,IV	0.525	0.735	.008	26	view →
UVM	OS	Tertile	III,IV	0.405	0.822	.007	24	view →
UCS	DFS	Tertile	IV	0.996	0.568	.036	24	view →
CESC	DFS	Median	II,III,IV	0.634	0.255	.011	20	view →
LIHC	OS	Median	II,III,IV	0.932	0.643	<.001	19	view →
SKCM	DFS	Median	II,III,IV	0.177	0.281	.003	17	view →
READ	OS	Tertile	All	0.983	0.850	.007	16	view →
MESO	OS	Quartile	II,III,IV	0.273	0.458	.015	14	view →
LUSC	OS	Quartile	All	0.537	0.369	.009	13	view →
PRAD	DFS	Tertile	All	0.902	0.708	.014	12	view →
PCPG	DFS	Quartile	All	0.572	0.902	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

PPIAP64–KIRP (OS)

Open the KIRP breakdown →