PPIAP58

Across TCGA pan-cancer cohorts, PPIAP58 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of PPIAP58’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where PPIAP58 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PPIAP58 is over-expressed in tumor.

LUAD, HNSC, and STAD are the cancer types where PPIAP58 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPIAP58 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	+0.365	<.001	5	view →
HNSC	All	All	+0.185	.005	5	view →
STAD	All	II,III,IV	+0.176	.003	5	view →
BRCA	All	All	+0.155	.001	4	view →
LIHC	All	All	+0.168	.001	3	view →
BLCA	Male	All	+0.323	.020	2	view →
CHOL	All	All	+0.246	.022	2	view →
LUSC	All	All	+0.162	.028	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

PPIAP58–LUAD

Open the LUAD breakdown →