PPIAP57

Across TCGA patient cohorts, PPIAP57 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,583 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAP57-associated GO terms across cancer lineages are Positive regulation of protein modification by small protein conjugation or removal, Hindbrain development, and Negative regulation of protein localization to nucleus. Each is linked with PPIAP57 in more than 4 cancer types. Because this analysis shows association rather than direction, both PPIAP57-to-partner and partner-to-PPIAP57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein modification by small protein conjugation or removal grouped by PPIAP57-low versus PPIAP57-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP57→partner) and Y-score (partner→PPIAP57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of protein modification by small protein conjugation or removal →	+0.151	+0.064	<.001	.006	3	5
STAD	Hindbrain development →	+0.091	+0.044	<.001	.004	3	4
STAD	Negative regulation of protein localization to nucleus →	+0.148	+0.048	<.001	.001	3	4
STAD	Regulation of proteolysis involved in protein catabolic process →	+0.161	+0.047	<.001	.002	3	4
STAD	Forebrain cell migration →	+0.081	+0.086	<.001	.001	3	4
STAD	Establishment of cell polarity →	+0.143	+0.044	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,583 associations by consensus.

Positive regulation of protein modification by small protein conjugation or removal by PPIAP57 expression — STAD

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