Q-omics provides the consensus-scored PPIAP57 profile across patient tissues and cancer cell-line models. PPIAP57 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in STAD. Additionally, PPIAP57 RNA expression shows 7,537 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight STAD, and COAD as cancer lineages where PPIAP57 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes PPIAP57 survival associations across molecular data types. PPIAP57 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

PPIAP57 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	STAD (78)	view →

This table ranks reproducible PPIAP57 RNA expression–survival associations across cancer types. High PPIAP57 expression shows unfavorable associations in STAD, SKCM, ESCA, BLCA, READ and LGG. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .006). Together, the overview and detailed table identify STAD as the clearest survival context for PPIAP57 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	III,IV	0.227	0.542	.006	78	view →
SKCM	DFS	Tertile	All	0.058	0.757	<.001	54	view →
ESCA	DFS	Tertile	III,IV	0.122	0.448	.005	45	view →
BLCA	DFS	Tertile	II,III,IV	0.180	0.519	.026	45	view →
READ	DFS	Tertile	III,IV	0.082	0.749	<.001	36	view →
LGG	DFS	Tertile	All	0.562	0.837	<.001	33	view →

Pink = unfavorable, green = favorable. all 11 lineages →

PPIAP57-STAD (OS)

Kaplan–Meier survival curve for PPIAP57 RNA expression in STAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with PPIAP57 in patient tissues and cancer cell lines. In patient samples, PPIAP57 shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7,537	COAD (3124)	view →
Function (RNA)	4,583	STAD (4048)	view →