PPIAP56

Across TCGA patient cohorts, PPIAP56 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,671 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAP56-associated GO terms across cancer lineages are Negative regulation of mRNA metabolic process, Mitochondrial electron transport, cytochrome c to oxygen, and Positive regulation of cell growth. Each is linked with PPIAP56 in more than 6 cancer types. Because this analysis shows association rather than direction, both PPIAP56-to-partner and partner-to-PPIAP56 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA metabolic process grouped by PPIAP56-low versus PPIAP56-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP56→partner) and Y-score (partner→PPIAP56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of mRNA metabolic process →	+0.075	+0.033	<.001	<.001	3	6
STAD	Mitochondrial electron transport, cytochrome c to oxygen →	+0.092	+0.040	<.001	.003	3	6
STAD	Positive regulation of cell growth →	+0.058	+0.029	<.001	.001	3	6
STAD	Protein O-linked mannosylation →	+0.049	+0.045	<.001	.003	2	7
STAD	Establishment of protein localization to membrane →	+0.084	+0.032	<.001	<.001	3	6
LGG	Vesicle-mediated transport in synapse →	+0.069	+0.017	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,671 associations by consensus.

Negative regulation of mRNA metabolic process by PPIAP56 expression — STAD

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