PPIAP56

Across TCGA pan-cancer cohorts, PPIAP56 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated PPIAP56 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PPIAP56 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPIAP56 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUAD show a favorable association.

UVM, ACC, and THCA are the cancer types where PPIAP56 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.275	0.770	.007	81	view →
ACC	OS	Tertile	All	0.129	0.631	.007	54	view →
THCA	OS	Tertile	III,IV	0.125	0.786	<.001	51	view →
BLCA	OS	Tertile	All	0.326	0.697	.002	45	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
PAAD	OS	Tertile	II,III,IV	1.000	0.362	.025	30	view →
KIRC	DFS	Tertile	III,IV	0.164	0.477	.019	24	view →
ESCA	OS	Tertile	All	0.211	0.876	.028	18	view →
PCPG	OS	Tertile	All	0.834	0.974	.029	18	view →
LIHC	DFS	Tertile	All	0.226	0.565	.001	18	view →
LUAD	DFS	Tertile	All	1.000	0.321	.018	12	view →
STAD	OS	Tertile	IV	0.111	0.433	.002	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

PPIAP56–UVM (DFS)

Open the UVM breakdown →