Across TCGA patient cohorts, PPIAP50 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,222 significant associations in total. THCA shows the largest number of these associations.

The most reproducible PPIAP50-associated GO terms across cancer lineages are Protein maturation by iron-sulfur cluster transfer, Proteasome assembly, and Ribosome assembly. Each is linked with PPIAP50 in more than 15 cancer types. Because this analysis shows association rather than direction, both PPIAP50-to-partner and partner-to-PPIAP50 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP50→partner) and Y-score (partner→PPIAP50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein maturation by iron-sulfur cluster transfer →	+0.041	+0.265	<.001	<.001	3	16
STAD	Proteasome assembly →	+0.043	+0.250	<.001	<.001	3	16
STAD	Ribosome assembly →	+0.037	+0.172	<.001	.001	3	15
STAD	Outer mitochondrial membrane organization →	+0.040	+0.245	<.001	<.001	3	15
LIHC	Cytochrome complex assembly →	+0.018	+0.097	<.001	<.001	3	14
LAML	Ribosomal large subunit assembly →	+0.042	+0.429	.004	.002	1	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,222 associations by consensus.

Exploration

PPIAP50 survival (RNA) · tumor vs normal (RNA) · all PPIAP50 data types