PPIAP50

Across TCGA pan-cancer cohorts, PPIAP50 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated PPIAP50 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PPIAP50 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP50 expression acts as an unfavorable survival marker, although some lineages such as ESCA and SKCM show a favorable association.

STAD, LIHC, and COAD are the cancer types where PPIAP50 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Quartile	III,IV	0.239	0.693	.002	67	view →
LIHC	OS	Tertile	III,IV	0.242	0.516	.004	59	view →
COAD	OS	Quartile	IV	0.373	0.732	<.001	49	view →
PAAD	DFS	Tertile	All	0.347	0.572	.005	47	view →
ACC	DFS	Median	All	0.320	0.760	<.001	42	view →
UCEC	OS	Median	All	0.540	0.783	<.001	36	view →
ESCA	DFS	Median	IV	0.634	0.205	.006	28	view →
SKCM	OS	Quartile	III,IV	0.649	0.281	.010	22	view →
LUSC	OS	Quartile	II,III,IV	0.559	0.314	.007	12	view →
UCS	DFS	Tertile	IV	0.981	0.442	.024	12	view →
OV	OS	Quartile	IV	0.812	0.484	.017	10	view →
THCA	DFS	Tertile	IV	1.000	0.607	.033	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

PPIAP50–STAD (OS)

Open the STAD breakdown →