PPIAP46

Across TCGA patient cohorts, PPIAP46 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,990 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPIAP46-associated GO terms across cancer lineages are Cellular respiration, Nucleoside phosphate biosynthetic process, and Protein folding. Each is linked with PPIAP46 in more than 23 cancer types. Because this analysis shows association rather than direction, both PPIAP46-to-partner and partner-to-PPIAP46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular respiration grouped by PPIAP46-low versus PPIAP46-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP46→partner) and Y-score (partner→PPIAP46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cellular respiration →	+0.048	+0.071	<.001	<.001	3	24
STAD	Nucleoside phosphate biosynthetic process →	+0.039	+0.072	<.001	<.001	3	21
STAD	Protein folding →	+0.043	+0.070	<.001	<.001	3	21
STAD	Mitochondrial membrane organization →	+0.047	+0.081	<.001	<.001	3	20
STAD	Nucleoside triphosphate metabolic process →	+0.048	+0.087	<.001	<.001	3	20
STAD	Regulation of DNA biosynthetic process →	+0.046	+0.061	<.001	.002	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,990 associations by consensus.

Cellular respiration by PPIAP46 expression — STAD

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