PPIAP32

Across TCGA pan-cancer cohorts, PPIAP32 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PPIAP32 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher PPIAP32 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPIAP32 expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

THCA, UCS, and TGCT are the cancer types where PPIAP32 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Quartile	II,III,IV	0.529	0.787	<.001	71	view →
UCS	DFS	Tertile	II,III,IV	0.538	0.177	.009	70	view →
TGCT	OS	Tertile	II,III,IV	0.670	1.000	.005	36	view →
BRCA	DFS	Tertile	III,IV	0.960	0.836	.001	33	view →
THYM	DFS	Quartile	III,IV	0.317	0.892	.002	27	view →
MESO	DFS	Tertile	IV	0.094	0.399	<.001	27	view →
DLBC	DFS	Quartile	III,IV	0.070	0.833	.014	26	view →
LUSC	DFS	Tertile	II,III,IV	0.824	0.654	.006	25	view →
BLCA	OS	Quartile	IV	0.317	0.504	.005	21	view →
KIRC	DFS	Quartile	IV	0.466	0.669	.014	20	view →
READ	DFS	Tertile	IV	0.158	0.668	.001	9	view →
UVM	DFS	Quartile	III,IV	0.286	0.654	.024	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PPIAP32–THCA (DFS)

Open the THCA breakdown →