PPIAP26

Across TCGA pan-cancer cohorts, PPIAP26 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated PPIAP26 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PPIAP26 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP26 expression acts as an unfavorable survival marker, although some lineages such as SKCM and DLBC show a favorable association.

STAD, KICH, and SKCM are the cancer types where PPIAP26 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	III,IV	0.543	0.718	.003	59	view →
KICH	DFS	Quartile	All	0.622	0.948	.002	39	view →
SKCM	OS	Quartile	III,IV	0.905	0.753	.004	34	view →
ACC	OS	Quartile	II,III,IV	0.348	0.730	.007	30	view →
DLBC	OS	Median	All	1.000	0.474	.009	14	view →
COAD	DFS	Tertile	IV	0.336	0.626	.008	13	view →
BLCA	DFS	Quartile	All	0.130	0.460	.014	10	view →
PAAD	DFS	Tertile	III,IV	0.152	0.821	.045	9	view →
CESC	DFS	Quartile	All	0.858	0.738	.027	6	view →
ESCA	OS	Tertile	IV	0.738	0.243	.024	6	view →
PRAD	DFS	Median	All	0.952	0.918	.035	4	view →
CHOL	OS	Tertile	All	1.000	0.534	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

PPIAP26–STAD (OS)

Open the STAD breakdown →