PPIAL4H

Across TCGA patient cohorts, PPIAL4H RNA expression is significantly associated with the go_rna of many other GO terms, with 6,154 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAL4H-associated GO terms across cancer lineages are ATP synthesis coupled electron transport, Positive regulation of DNA repair, and Proton motive force-driven ATP synthesis. Each is linked with PPIAL4H in more than 16 cancer types. Because this analysis shows association rather than direction, both PPIAL4H-to-partner and partner-to-PPIAL4H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP synthesis coupled electron transport grouped by PPIAL4H-low versus PPIAL4H-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAL4H→partner) and Y-score (partner→PPIAL4H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	ATP synthesis coupled electron transport →	+0.072	+0.185	.003	<.001	3	16
STAD	Positive regulation of DNA repair →	+0.040	+0.102	<.001	<.001	3	16
ESCA	Proton motive force-driven ATP synthesis →	+0.080	+0.227	.001	<.001	3	16
ESCA	Oxidative phosphorylation →	+0.076	+0.196	.001	<.001	3	15
ESCA	Aerobic respiration →	+0.052	+0.160	.009	<.001	2	16
ESCA	ATP biosynthetic process →	+0.073	+0.187	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,154 associations by consensus.

ATP synthesis coupled electron transport by PPIAL4H expression — ESCA

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