PPIAL4H

Across TCGA pan-cancer cohorts, PPIAL4H RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of PPIAL4H’s most consistent transcriptional readouts.

The strongest signal is observed in rectum adenocarcinoma (READ), where PPIAL4H RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PPIAL4H is over-expressed in tumor, although a few such as UCEC show the opposite, repressed pattern.

READ, UCEC, and STAD are the cancer types where PPIAL4H tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPIAL4H RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
READ	All	III,IV	+0.114	.001	5	view →
UCEC	All	II,III,IV	−0.154	.017	4	view →
STAD	All	II,III,IV	+0.136	.036	2	view →
BLCA	Male	All	+0.092	.031	2	view →
KIRC	Male	All	+0.036	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

PPIAL4H–READ

Open the READ breakdown →