PPIAL4D

Across TCGA patient cohorts, PPIAL4D RNA expression is significantly associated with the protein abundance of many other proteins, with 1,339 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPIAL4D-associated proteins across cancer lineages are MVD_S211, NPC1, and ARHGAP12_S592. Each is linked with PPIAL4D in more than 1 cancer types. Because this analysis shows association rather than direction, both PPIAL4D-to-partner and partner-to-PPIAL4D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIAL4D versus MVD_S211 in CCRCC, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAL4D→partner) and Y-score (partner→PPIAL4D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MVD_S211 →	-0.373	-0.109	.008	.001	3	2
BRCA	NPC1 →	-0.396	-0.115	.003	.002	3	2
PDAC	ARHGAP12_S592 →	-0.664	-0.060	.007	.005	3	2
CCRCC	HLA-C →	+0.529	+0.087	<.001	.002	3	2
OV	ZRANB2_S280 →	-1.260	-0.068	.007	.002	3	1
OV	AXIN1_S486 →	+1.549	+0.093	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,339 associations by consensus.

PPIAL4D vs MVD_S211 — CCRCC

Explore this scatter interactively →