PPIAL4D

Across TCGA patient cohorts, PPIAL4D RNA expression is significantly associated with the go_rna of many other GO terms, with 4,663 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAL4D-associated GO terms across cancer lineages are Mitochondrial respiratory chain complex assembly, Ribosomal large subunit assembly, and UTP metabolic process. Each is linked with PPIAL4D in more than 5 cancer types. Because this analysis shows association rather than direction, both PPIAL4D-to-partner and partner-to-PPIAL4D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial respiratory chain complex assembly grouped by PPIAL4D-low versus PPIAL4D-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAL4D→partner) and Y-score (partner→PPIAL4D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial respiratory chain complex assembly →	+0.044	+0.096	<.001	<.001	3	6
STAD	Ribosomal large subunit assembly →	+0.038	+0.089	<.001	<.001	3	5
STAD	UTP metabolic process →	+0.038	+0.120	<.001	<.001	3	5
STAD	Regulation of mitochondrial transcription →	+0.032	+0.084	<.001	<.001	3	5
STAD	Anaphase-promoting complex-dependent catabolic process →	+0.033	+0.103	<.001	<.001	3	5
STAD	Mitochondrial translation →	+0.047	+0.128	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,663 associations by consensus.

Mitochondrial respiratory chain complex assembly by PPIAL4D expression — STAD

Explore this box plot interactively →