PPIAL4C

Across TCGA patient cohorts, PPIAL4C RNA expression is significantly associated with the protein abundance of many other proteins, with 6,923 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPIAL4C-associated proteins across cancer lineages are VAV1, SEPTIN1, and SH2D1A. Each is linked with PPIAL4C in more than 3 cancer types. Because this analysis shows association rather than direction, both PPIAL4C-to-partner and partner-to-PPIAL4C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIAL4C versus VAV1 in LSCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAL4C→partner) and Y-score (partner→PPIAL4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VAV1 →	+0.442	+0.326	<.001	<.001	3	4
LSCC	SEPTIN1 →	+0.789	+0.350	<.001	<.001	3	4
LSCC	SH2D1A →	+0.772	+0.318	<.001	<.001	3	4
CCRCC	IKZF1_S445 →	+0.790	+0.330	<.001	.002	3	4
LSCC	IL16_S845 →	+0.818	+0.277	<.001	.001	3	4
LSCC	CELF2 →	+0.428	+0.253	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,923 associations by consensus.

PPIAL4C vs VAV1 — LSCC

Explore this scatter interactively →