PPIAL4C

Across TCGA patient cohorts, PPIAL4C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,989 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAL4C-associated GO terms across cancer lineages are Mitochondrial cytochrome c oxidase assembly, Mitochondrial translation, and Ribosomal large subunit assembly. Each is linked with PPIAL4C in more than 12 cancer types. Because this analysis shows association rather than direction, both PPIAL4C-to-partner and partner-to-PPIAL4C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial cytochrome c oxidase assembly grouped by PPIAL4C-low versus PPIAL4C-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAL4C→partner) and Y-score (partner→PPIAL4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial cytochrome c oxidase assembly →	+0.035	+0.089	<.001	<.001	3	13
STAD	Mitochondrial translation →	+0.049	+0.113	<.001	<.001	3	12
STAD	Ribosomal large subunit assembly →	+0.046	+0.101	<.001	<.001	3	11
STAD	Protein deneddylation →	+0.036	+0.088	<.001	<.001	3	11
STAD	Ribosome assembly →	+0.049	+0.105	<.001	<.001	3	11
STAD	Cytoplasmic translation →	+0.056	+0.087	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,989 associations by consensus.

Mitochondrial cytochrome c oxidase assembly by PPIAL4C expression — STAD

Explore this box plot interactively →