PPFIBP1

Across TCGA patient cohorts, PPFIBP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,640 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPFIBP1-associated proteins across cancer lineages are PPFIBP1_S540, PPFIBP1_S579, and PPFIBP1_S466. Each is linked with PPFIBP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PPFIBP1-to-partner and partner-to-PPFIBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPFIBP1 versus PPFIBP1_S540 in BRCA, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPFIBP1→partner) and Y-score (partner→PPFIBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPFIBP1_S540 →	+0.971	+0.618	<.001	<.001	3	9
OV	PPFIBP1_S579 →	+0.389	+0.958	.001	<.001	3	9
BRCA	PPFIBP1_S466 →	+0.910	+0.721	<.001	<.001	3	8
BRCA	CRTAP →	+0.601	+0.729	<.001	<.001	3	8
BRCA	PLOD1 →	+0.582	+0.717	<.001	<.001	3	8
PDAC	PPFIBP1_S37 →	+0.746	+0.592	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,640 associations by consensus.

PPFIBP1 vs PPFIBP1_S540 — BRCA

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