PPFIBP1

Across TCGA patient cohorts, PPFIBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,649 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PPFIBP1-associated genes across cancer lineages are FRMD6, TIMP3, and MYL9. Each is linked with PPFIBP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PPFIBP1-to-partner and partner-to-PPFIBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPFIBP1 versus FRMD6 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPFIBP1→partner) and Y-score (partner→PPFIBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FRMD6 →	+0.998	+0.562	<.001	<.001	3	10
OV	TIMP3 →	+1.559	+0.336	<.001	<.001	3	9
GBM	MYL9 →	+1.372	+0.601	<.001	<.001	3	9
BRCA	SYDE1 →	+0.878	+0.387	<.001	<.001	3	9
BRCA	MRC2 →	+1.124	+0.422	<.001	<.001	3	9
BRCA	DSE →	+0.680	+0.397	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,649 associations by consensus.

PPFIBP1 vs FRMD6 — BRCA

Explore this scatter interactively →