PPFIBP1

Across TCGA cell cohorts, PPFIBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,492 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPFIBP1-associated GO terms across cancer lineages are Cortical microtubule organization, Regulation of cell-substrate junction assembly, and Establishment of RNA localization. Each is linked with PPFIBP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both PPFIBP1-to-partner and partner-to-PPFIBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cortical microtubule organization grouped by PPFIBP1-low versus PPFIBP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPFIBP1→partner) and Y-score (partner→PPFIBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cortical microtubule organization →	+0.167	+1.370	<.001	<.001	3	17
BONE	Regulation of cell-substrate junction assembly →	+0.161	+1.491	<.001	<.001	3	15
STOMACH	Establishment of RNA localization →	+0.105	+1.576	.002	.004	3	15
BONE	Regulation of focal adhesion assembly →	+0.161	+1.491	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.062	+1.601	.002	<.001	3	15
LARGE_INTESTINE	Heterochromatin formation →	+0.066	+1.868	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,492 associations by consensus.

Cortical microtubule organization by PPFIBP1 expression — OESOPHAGUS

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