PPFIA3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PPFIA3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,329 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPFIA3-associated genes across cancer lineages are SNORA63C, ACSM3, and ALDH3B1. Each is linked with PPFIA3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PPFIA3-to-partner and partner-to-PPFIA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPFIA3 versus SNORA63C in HNSC, with a Pearson correlation of -0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPFIA3→partner) and Y-score (partner→PPFIA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCSNORA63C →-1.280-0.479<.001.00233
LUADACSM3 →-0.888-0.700.002.00133
LUADALDH3B1 →-0.879-0.592.002.00633
UCECLIFR →-1.301-0.748.003.00133
HNSCFABP3 →-0.909-0.406<.001.00433
UCECF8 →-0.672-0.756.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,329 associations by consensus.

PPFIA3 vs SNORA63C — HNSC

Per-sample scatter of PPFIA3 vs SNORA63C in HNSC (Pearson r = -0.25).

Explore this scatter interactively →

Exploration