PPFIA1

Across TCGA patient cohorts, PPFIA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,355 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PPFIA1-associated proteins across cancer lineages are PPFIA1_S708, FN1, and SMC4. Each is linked with PPFIA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PPFIA1-to-partner and partner-to-PPFIA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPFIA1 versus PPFIA1_S708 in BRCA, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPFIA1→partner) and Y-score (partner→PPFIA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPFIA1_S708 →	+0.838	+0.969	<.001	<.001	3	5
OV	FN1 →	+0.958	+0.431	.004	.005	2	5
LUAD	SMC4 →	+0.446	+0.393	.002	.002	3	4
LSCC	SNRNP200 →	+0.267	+0.858	<.001	.002	3	4
LUAD	SRSF6_S316 →	+1.108	+0.589	<.001	.001	3	4
LSCC	STIP1_S481 →	+0.639	+0.758	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,355 associations by consensus.

PPFIA1 vs PPFIA1_S708 — BRCA

Explore this scatter interactively →