PPEF2

Across TCGA patient cohorts, PPEF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,897 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPEF2-associated GO terms across cancer lineages are Vacuole organization, TORC1 signaling, and Endosomal transport. Each is linked with PPEF2 in more than 25 cancer types. Because this analysis shows association rather than direction, both PPEF2-to-partner and partner-to-PPEF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuole organization grouped by PPEF2-low versus PPEF2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPEF2→partner) and Y-score (partner→PPEF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Vacuole organization →	+0.071	+0.142	<.001	<.001	3	26
ESCA	TORC1 signaling →	+0.096	+0.162	<.001	<.001	3	26
STAD	Endosomal transport →	+0.071	+0.147	<.001	<.001	3	25
STAD	Regulation of intrinsic apoptotic signaling pathway →	+0.070	+0.147	<.001	<.001	3	25
STAD	Mitochondrial membrane organization →	+0.066	+0.132	<.001	<.001	3	25
STAD	Autophagosome organization →	+0.071	+0.130	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,897 associations by consensus.

Vacuole organization by PPEF2 expression — STAD

Explore this box plot interactively →