PPEF1

Across TCGA patient cohorts, PPEF1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,116 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPEF1-associated genes across cancer lineages are RASSF2, NALCN, and RGCC. Each is linked with PPEF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPEF1-to-partner and partner-to-PPEF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPEF1 versus RASSF2 in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPEF1→partner) and Y-score (partner→PPEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RASSF2 →	+0.746	+0.493	<.001	.002	3	1
GBM	NALCN →	+0.862	+0.472	.004	<.001	3	1
GBM	RGCC →	+0.761	+0.519	<.001	<.001	3	1
GBM	TJP1 →	+0.465	+0.522	<.001	<.001	3	1
GBM	SLC1A5 →	-0.838	-0.423	.003	.002	3	1
GBM	COBL →	+0.812	+0.337	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,116 associations by consensus.

PPEF1 vs RASSF2 — GBM

Explore this scatter interactively →