PPEF1

Across TCGA cell cohorts, PPEF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,868 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPEF1-associated GO terms across cancer lineages are Regulation of response to wounding, Digestive system process, and Positive regulation of chemotaxis. Each is linked with PPEF1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PPEF1-to-partner and partner-to-PPEF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of response to wounding grouped by PPEF1-low versus PPEF1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPEF1→partner) and Y-score (partner→PPEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of response to wounding →	-0.059	-0.462	<.001	.002	3	8
SKIN	Digestive system process →	-0.128	-0.460	.006	.007	2	8
BONE	Positive regulation of chemotaxis →	-0.126	-0.357	<.001	.001	3	7
BONE	Response to mechanical stimulus →	-0.084	-0.485	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Blood coagulation, extrinsic pathway →	-1.505	-0.468	<.001	.002	3	7
SKIN	Mesoderm development →	-0.088	-0.425	.004	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,868 associations by consensus.

Regulation of response to wounding by PPEF1 expression — BLOOD_Leukemia

Explore this box plot interactively →