PPDPFL

Across TCGA pan-cancer cohorts, PPDPFL Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PPDPFL data layer compared with 19 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher PPDPFL Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPDPFL expression acts as an unfavorable survival marker.

OV, READ, and SKCM are the cancer types where PPDPFL Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	All	0.142	0.541	.002	12	view →
READ	OS	Median	II,III,IV	0.187	0.644	.023	9	view →
SKCM	OS	Median	III,IV	0.232	0.697	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PPDPFL–OV (DFS)

Open the OV breakdown →