PPDPFL

Across TCGA patient cohorts, PPDPFL RNA expression is significantly associated with the go_rna of many other GO terms, with 6,214 significant associations in total. SARC shows the largest number of these associations.

The most reproducible PPDPFL-associated GO terms across cancer lineages are Aerobic respiration, Ribose phosphate biosynthetic process, and Oxidative phosphorylation. Each is linked with PPDPFL in more than 10 cancer types. Because this analysis shows association rather than direction, both PPDPFL-to-partner and partner-to-PPDPFL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by PPDPFL-low versus PPDPFL-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPDPFL→partner) and Y-score (partner→PPDPFL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Aerobic respiration →	+0.063	+0.138	<.001	<.001	2	11
DLBC	Ribose phosphate biosynthetic process →	+0.048	+0.235	.006	.003	2	10
STAD	Oxidative phosphorylation →	+0.064	+0.120	<.001	<.001	2	10
STAD	NADH dehydrogenase complex assembly →	+0.057	+0.136	<.001	<.001	3	9
ESCA	Glutamine metabolic process →	+0.044	+0.065	<.001	.008	1	10
ESCA	Cellular response to UV →	+0.055	+0.045	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,214 associations by consensus.

Aerobic respiration by PPDPFL expression — STAD

Explore this box plot interactively →