PPDPFL

Across TCGA patient cohorts, PPDPFL mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPDPFL-associated genes across cancer lineages are Basophils, Neurons, and CD8+ Tem. Each is linked with PPDPFL in more than 1 cancer types. Because this analysis shows association rather than direction, both PPDPFL-to-partner and partner-to-PPDPFL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basophils grouped by PPDPFL-low versus PPDPFL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPDPFL→partner) and Y-score (partner→PPDPFL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Basophils →	+0.207	+3.169	.026	.019	3	2
SKCM	Neurons →	+0.026	+2.478	.004	.011	3	1
UCEC	CD8+ Tem →	+0.004	+4.896	<.001	.036	3	1
UCEC	CLP →	-0.074	-3.127	.032	.020	3	1
UCEC	CD8+ naive T-cells →	-0.031	-3.127	.035	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Basophils by PPDPFL expression — UCEC

Explore this box plot interactively →