PPDPF

Across TCGA patient cohorts, PPDPF RNA expression is significantly associated with the go_rna of many other GO terms, with 7,161 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPDPF-associated GO terms across cancer lineages are COPII-coated vesicle cargo loading, Positive regulation of mRNA 3'-end processing, and Biological process involved in interaction with symbiont. Each is linked with PPDPF in more than 22 cancer types. Because this analysis shows association rather than direction, both PPDPF-to-partner and partner-to-PPDPF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle cargo loading grouped by PPDPF-low versus PPDPF-high in MESO.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPDPF→partner) and Y-score (partner→PPDPF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
MESO	COPII-coated vesicle cargo loading →	-0.061	-0.514	<.001	<.001	3	23
SKCM	Positive regulation of mRNA 3'-end processing →	-0.051	-0.523	<.001	<.001	3	23
STAD	Biological process involved in interaction with symbiont →	-0.032	-0.562	<.001	<.001	3	22
READ	Mitochondrial translational elongation →	-0.047	-0.883	<.001	<.001	3	22
ESCA	Actin polymerization-dependent cell motility →	-0.066	-0.505	<.001	<.001	3	22
UVM	Obsolete mRNA methylation →	-0.048	-0.624	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,161 associations by consensus.

COPII-coated vesicle cargo loading by PPDPF expression — MESO

Explore this box plot interactively →