PPDPF

Across TCGA patient cohorts, PPDPF protein abundance is significantly associated with the RNA expression of many other genes, with 11,034 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPDPF-associated genes across cancer lineages are IKBKB, GTPBP4, and PPM1G. Each is linked with PPDPF in more than 2 cancer types. Because this analysis shows association rather than direction, both PPDPF-to-partner and partner-to-PPDPF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPDPF versus IKBKB in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPDPF→partner) and Y-score (partner→PPDPF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IKBKB →	+0.789	+0.501	<.001	<.001	3	3
BRCA	GTPBP4 →	-0.579	-0.406	<.001	<.001	3	3
BRCA	PPM1G →	-0.336	-0.460	.008	.001	3	3
BRCA	OSCP1 →	+0.687	+0.450	<.001	<.001	3	3
LSCC	CD274 →	-0.910	-0.216	.003	.006	3	3
PDAC	GNMT →	+1.233	+0.401	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,034 associations by consensus.

PPDPF vs IKBKB — BRCA

Explore this scatter interactively →