PPDPF

Across TCGA cell cohorts, PPDPF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,391 significant associations in total. CNS shows the largest number of these associations.

The most reproducible PPDPF-associated GO terms across cancer lineages are 'de novo' IMP biosynthetic process, RNA methylation, and 'de novo' AMP biosynthetic process. Each is linked with PPDPF in more than 8 cancer types. Because this analysis shows association rather than direction, both PPDPF-to-partner and partner-to-PPDPF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' IMP biosynthetic process grouped by PPDPF-low versus PPDPF-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPDPF→partner) and Y-score (partner→PPDPF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	'de novo' IMP biosynthetic process →	-0.141	-1.032	<.001	.002	3	9
CNS	RNA methylation →	-0.043	-1.149	<.001	<.001	3	8
OVARY	'de novo' AMP biosynthetic process →	-0.101	-1.050	.002	<.001	3	8
BREAST	L-glutamine catabolic process →	-0.168	-0.824	<.001	<.001	3	8
PANCREAS	Regulation of peptidyl-tyrosine phosphorylation →	+0.078	+0.845	<.001	<.001	3	7
URINARY_TRACT	Transcription initiation at mitochondrial promoter →	-0.165	-1.626	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,391 associations by consensus.

'de novo' IMP biosynthetic process by PPDPF expression — OVARY

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