PPCDC

Across TCGA patient cohorts, PPCDC RNA expression is significantly associated with the RNA expression of many other genes, with 19,122 significant associations in total. UVM shows the largest number of these associations.

The most reproducible PPCDC-associated genes across cancer lineages are COMMD4, MRPS11, and ZFYVE19. Each is linked with PPCDC in more than 32 cancer types. Because this analysis shows association rather than direction, both PPCDC-to-partner and partner-to-PPCDC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPCDC versus COMMD4 in DLBC, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPCDC→partner) and Y-score (partner→PPCDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	COMMD4 →	+0.972	+1.000	<.001	<.001	3	33
ACC	MRPS11 →	+0.867	+0.811	<.001	<.001	3	33
ACC	ZFYVE19 →	+0.974	+0.860	<.001	<.001	3	33
ACC	CLN6 →	+0.935	+0.930	<.001	<.001	3	33
CHOL	UBL7 →	+0.912	+0.871	<.001	<.001	3	32
ACC	HDDC3 →	+1.228	+1.005	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,122 associations by consensus.

PPCDC vs COMMD4 — DLBC

Explore this scatter interactively →